**11. Carbapenems**

Resistance to Meropenem or Imipenem among *Abiotrophia* and *Granulicatella species* is rare. Review of 132 isolates by Albierti showed 100% sensitivity to Meropenem and Imipenem (MIC ≤0.06 μg/ml for both antibiotics) [62]. Touhy et al. [66] found that 3 isolates of *A. adiacens* (out of 27 total isolates) and 7 isolates of *G. defectiva* (out of 12 total isolates) had increased MICs of Meropenem (0.5 μg/ml). These isolates also had penicillin MICs ≥0.5 μg/ml. One of their isolates of *A*. *adiacens* had a high MIC for Meropenem (MIC of 1 μg/ml) which was isolated from a patient with suspected intervertebral disc space infection who had received a prolonged course of various antibiotics including beta-lactams. This particular isolate was also resistant to penicillin and ceftriaxone (MICs ≥8 μg/ml).
