**6. Lysergic acid diethylamide and psilocybin**

Lysergic acid diethylamide (LSD) and psilocybin "magic mushrooms" are commonly used hallucinogenic agents in developed countries. LSD is about 100 times more potent than psilocybin. Their mechanisms of action are complex and include agonist, partial agonist, and antagonist effects at various serotonin, dopaminergic, and adrenergic receptors. The adrenergic effects are usually mild and do not produce the profound sympathetic storms that can occur after taking cocaine, amphetamine, or ecstasy. Besides common sinus tachycardia, cardiovascular complications are rarely serious, although occasional instances of supraventricular tachyarrhythmias and myocardial infarction have been reported [61, 62].
