3. Conclusion

This book chapter indicates that there has been an increase in the search of terpenes with antiinflammatory activity in recent years. This fact indicates that terpenes are a topic of interest. The possible mechanisms involved in the anti-inflammatory effects of the terpenes are pointing out on the inhibition of NF-κB, TNF-α, PGE2, and pro-inflammatory cytokines such as IL-6. NF-κB is one of the current targets for the development of new anti-inflammatory drugs [71]. In addition, the molecular targets of terpenes are highly desirable to find target-specific antiinflammatory drugs. The mechanism of action of many terpenes remains to be studied. The combination of terpenes with high anti-inflammatory activity and with studied mechanism of action and currently used drugs could be another strategy for further anti-inflammatory therapy.
