*2.13.1. Salvia africana-lutea*

*2.12.13. Plectranthus strigosus*

**2.13.** *Salvia* **genus**

26 Terpenes and Terpenoids

9 abietanes (parviflorones A (**183**), B (**184**), C (**185**), D (**114**), E (**186**), F (**115**), G (**187**), and H (**188**) [83], and hinokiol (**189**)) [84]), 3 kauranes (*ent*-16-kauren-19-ol (**190**), *ent*-16-kauren-19 oic acid (**191**), xylopic acid (**192**), xylopinic acid (**193**)), and 2 sesquiterpens (4*β*,6*β*-dihydroxy-1*α*,5*β*(H)-guai-9-ene (**194**) 4*β*,6*β*-dihydroxy-1*α*,5*β*(H)-guai-10(14)-ene (**195**)), were isolated [84]. A bioactivity study revealed herpetic inhibitory properties for (**190**) and (**191**) [84].

The genus *Salvia* is known as sage and is the largest genus in Lamiaceae, comprising over 900 species distributed throughout the world. *Salvia is* represented by 30 species in SA, distributed mainly in great cape region. The chemistry of *Salvia* is rich in diterpenoids and different skeletons have been reported, also, many members of this genus is well known for its curative

and medicinal properties like *S. officinalis* and *S. miltiorrhiza*.

Carnosol (**196**), rosmadial (**197**), and carnosic acid (**198**-characterized as its methyl ester) were isolated. Compound **198** exhibited potent activity against *M. tuberculosis* and cytotoxic activity against a breast (MCF-7) human cancer cell line [45].
