*2.12.6. Plectranthus fruticosus*

*Plectranthus fruticosus* cultivated in Porugal afforded 4 labdanes, *ent*-labda-8(17),12Z,14-trien-2*β*-ol (**121**),*ent*-2*α*-acetoxylabda-8(17),12*Z*,14-trien-3*β*-ol (**122**), ent-3*β*-acetoxylabda-8(17),

12*Z*,14-trien-2*α*-ol (**123**),3*β*-acetoxylabda-8(17),12*E*,14-trien-2*α*-ol (**124**), 10 kauranes (*ent*-12*β*acetoxy-15*β*,16*β*-epoxykauran-19-oic acid (**125**), *ent*-7*β*-hydroxy-15*β*,16*β*-epoxykauran-19-oic acid (**126**), *ent*-15*β*,16*β*-epoxykauran-19-oic acid (**127**), *ent*-15*β*,16*β*-epoxykauran-19-ol (**128**), *ent*-12*β*-acetoxy-15*β*-hydroxykaur-16-en-19-oic acid (**129**), *ent*-12*β*-acetoxy-7*β*-hydroxykaur-16-en-19-oic acid (**130**),methyl ent-12*β*-acetoxy-16-kauren-19-oate (**131**), *ent*-7*β*-hydroxykaur-15-en-19-oic acid (**132**), methyl *ent*-12*β*-acetoxy-7*β*-hydroxykaur-15-en-19-oate acid (**133**), *ent*-12*β*-acetoxy-17-oxokaur-15-en-19-oic acid (**134**), methyl *ent*-12*β*-acetoxy-15-kauren-19 oate (**135**), additionally, armendrance (**136**), caryophyllene *α*-oxide (**137**), ursolic/oleanolic acids (2,1 mixture) *β*-sitosterol, stigmasta-5,22*E*-dien-3*β*-ol, and *β*-amyrin. Some of the compounds showed moderate anti-*staphylococcus* activity [58, 59]. *P. fruticosus* growing in India showed abietane diterpene pattern and 7*α*-acetoxy-6*β*-hydroxyroyleanone (**102**), 6,7-dehydroroyleanone (**138**) and 7*α*,6*β*-dihydroxyroyleanone (**139**) were isolated [60].
