**3. KCNMA1: STRING analysis**

In order to understand the possible interactions of *KCNMA1* with other genes and molecules, we used the tool **STRING 9.1.** It is a database consisting of known and possible protein– protein interactions with a gene of interest. The gene may have a direct (physical) or indirect (functional) association with other molecules. With this tool we can easily identify possible interaction of *KCNMA1* with other associated molecules. We can derive detailed information

**Figure 2.** STRING 9.1 software-derived possible association of *KCNMA1* with top 20 most interacting genes.

of the protein being investigated as well as its associated molecules, crystal structure of the proteins with its PDB ID, and combined score [confidence score, neighborhood score, fusion score, homology score] on the basis of some parameters like experimental results, text-mining, co expression, databases, and co-occurrence (**Figure 2**).
