**8. Decellularized cardiac tissues and stem cells**

There are reports of fabricated decellularized cardiac tissue used as potential scaffolds. For example, human cardiac extracellular cell matrix sheets have been reported to be seeded with mesenchymal stem cells and cardiomyocytes by [56]. The authors concluded that the MSCcardiomyocyte-derived scaffold efficiently improved and stimulates cardiac tissue regeneration. In another report by [57], decellularized engineered heart valve was successfully implanted for reconstruction of the right ventricular outflow tract. The authors concluded that via echocardiography, the implanted heart valve demonstrated normal physiological pressure gradient after 10 years, with no record of calcification and, in addition, it exhibited an excellent hemodynamic performance.
