*2.1.3. Reverse phase protein arrays*

In these arrays, biological samples, tissues and cell lysates are printed onto array surface.- The detection is accomplished by antibodies link with specific proteins, and then link- with another antibody with fluorescence. They offers the potential for rapid comparison- of the levels of such proteins present among a significant number of samples on a single- array [7, 8].

The problem is the interaction of the lysate matrix, therefore validated antibodies should demonstrate no cross-reactivity toward other biomolecules of the lysate (**Figure 3**).

**Figure 3.** Arrays according to their nature of the capturing agent.
