**3.2.3.2 Impact of tumour size on renal function**

In the same study of Porpiglia (Porpiglia et al., 2010), small and large tumours groups had comparable preoperative serum creatinin and estimated GFR. On the 5th post-operative day, elevation of serum creatinin level was not significantly higher in the large tumour group, but deterioration of eGFR was statistically significant (p > 0.004).

The size of the tumour had no significant impact on the warm ischemia time (Porpiglia et al., 2010).

In large tumours, they recorded 4 cases (12%) with CKD progression, but these could not be explained by a longer warm ischemia time.

#### **3.2.3.3 Impact of tumour size on oncologic outcome**

Comparable to Russo in open partial nephrectomy, Porpiglia (Porpiglia et al., 2010) had a higher PSM rate in small tumours. Thus it appears that, as seen in open NSS, tumour size does not impact on PSM risk in the laparoscopic approach.
