**6. Measurement of liver volume from neonates to the elderly**

Total liver volume, the basic unit of liver function, is an important factor to evaluate the resectability of liver cancer. There have been many studies of the total liver volume and necessary remnant liver volume in adult patients but only a few reports regarding liver volume in children. Because measured total liver volume has been proposed as the golden standard of liver volume for preoperative surgical plan, we tried to summarize the average total liver volume of Chinese patients of different ages, from neonates to the elderly.

Upper abdominal CT films from 1456 children (enhanced CT 837, plain CT 619) aged 1 day to 100 years were selected. None had any history of liver disease, and CT had been performed

Imaging Evaluation of Liver Tumors in Pediatric Patients http://dx.doi.org/10.5772/intechopen.73855 67

The Human Digital Liver Database (HDLD) was established by the Affiliated Hospital of Qingdao University and Hisense Company, aiming to collect digital liver from neonates, children, adults, and the elderly, from normal livers, livers with cancer, and simulated livers resected using Hisense CAS. The link of the HDLD is http://www.hdldb.net, which now is only available in Chinese (the English version is being translated now). The HDLD will show the digital liver in image and video form. All visitors could study the updated clinical cases at any angle of reconstructed 3D digital liver, including the vascular system, anatomical differences in the liver, and the correlation between vascular and liver tumors. The HDLD will also provide the intra-operation video comparing to the preoperative surgical plan, to help doctors and medical students better understand the anatomy and surgical procedure of pediatric liver resection, especially for patients with giant liver tumors

Vascular anatomical variation and total liver volume are two of the more important factors that surgeons consider when making surgical plans. We have collected thousands of CT scan data from across the nation. We would like to establish a digital liver database showing the reconstructed digital liver and separate these digital livers into different groups according to the anatomical variations in liver vasculature and liver volume (**Figure 9**). The Dong's Digital Liver Classification was established based on our collection of digital livers. We believe that a normal digital liver database may serve as an important reference for surgeons all around

for other clinical purposes. The patients were divided into 26 groups by age (**Table 1**).

**7. Human Digital Liver Database**

**7.1. Normal children and adult digital liver database**

(**Figure 9**).

world.

**Figure 9.** The Human Digital Liver Database.


**Table 1.** Standard liver volume range (X ± S, cm<sup>3</sup> ). Upper abdominal CT films from 1456 children (enhanced CT 837, plain CT 619) aged 1 day to 100 years were selected. None had any history of liver disease, and CT had been performed for other clinical purposes. The patients were divided into 26 groups by age (**Table 1**).
