**2. Search strategy**

A literature search was performed on the *PubMed* database of the *US National Library of Medicine* and *Scholar Google*. We searched for articles published between January 2010 and March 2018, using the following keywords or associations: "*drug-induced neutropenia,*" "*drug-induced agranulocytosis,*" "*idiosyncratic neutropenia*" and "*idiosyncratic agranulocytosis*"; restrictions included: English- or French-language publications; published from January 1, 2010 to February 31, 2018; human subjects; clinical trials, review articles or guidelines. All of the English and French abstracts were reviewed by at least two senior researchers from our work group (*GRoupes d'Etudes des Agranulocytoses médicamenTeuses* (GREAT) des *Hôpitaux Universitaires de Strasbourg* (HUS), Strasbourg, France). After rigorous selection, only 15 papers were selected and analyzed. The latter was used to write this paper in the form of a short narrative review.

*American Society of Hematology* educational books, textbooks of Hematology and Internal medicine, and information gleaned from international meetings were also used.
