**Author details**

the effects of metabolic disorders on the development of cognitive disorders in patients presenting the abovementioned disorder. They concluded that chronic hyperglycemia and glucose variability are risk factors for the development of cognitive dysfunction, which confirm the need for more severe compensation of the disease. They also highlighted: "For type 1 diabetic patients with unsatisfactory compensation of carbohydrate metabolism the neuro-

In the chapter: Dementia Friendly Assistive Brotherhood Communities, authors from Bournemouth University in United Kingdom highlighted the usability of an assistive software application developed for 8 patients living with dementia (PWLD) and 40 volunteers at

Overall, the PWLD showed great interest in all the functionalities of the assistive brotherhood community application and were keen to adopt it permanently in their daily life activities. The PWLD specifically appreciated the increased socialization opportunities through the use of assistive brotherhood community application. The implementation of assistive brotherhood community application in the lives of the PWD will increase their confidence, self-

Another important chapter on Re-framing and Re-thinking Dementia in the Correctional Setting is written by two authors from University of Adelaide and University of South Australia. They raise the concern about the aging population in the Australian correctional setting. They highlighted the increasingly complex healthcare needs in the prisoner population who present with poorer physical, social, and mental health than the general population, and they also concluded that healthcare services within the correctional environment needs to match that in the general community and this requires the development of policies to support

One chapter written by two Korean colleagues from Korea Institute of Science and Technology cover the most relevant aspects of Tau in Tauopathies that leads to Cognitive Disorders and in Cancer. They refer Tau as a copious microtubule-associated protein mainly expressed in neurons; it is also expressed in non-neuronal cell. Tauopathies are neurodegenerative diseases occurring mostly within the neuronal and glial cells of the central nervous system with a conspicuous tau pathology. Tau might have significant functions in non-neuronal cells. In this

Nowadays, some drugs used for the treatment of cancer are also used for the treatment of different neurological disorders like Parkinson's disease and AD. They said that Nilotinib is an FDA-approved protein tyrosine kinase inhibitor (TKI)—used for the treatment of chronic myeloid leukemia but it also targets AD and produces neuroinflammation and misfolded proteins that ultimately reduce cognitive damage. In Parkinson's disease, nilotinib triggers autophagy to remove hyperphosphorylated tau from the brain before they accumulate as

The hypothalamus plays a central role in autonomic functions, including the generation and control of the circadian rhythms, the thermoregulation, the homeostasis of proteins, the maintenance of energy supply and the feeding behavior. Five authors from Aristotelian University,

staff to put processes in place that will improve health outcomes for prisoners.

chapter, authors describe the associations between tauopathies and cancer.

physiological tests looking for cognitive decline should be done."

5 different cities of Pakistan.

10 Cognitive Disorders

esteem, and independence.

plaques.

Humberto Foyaca Sibat<sup>1</sup> \* and Lourdes de Fátima Ibañez Valdés<sup>2</sup>

\*Address all correspondence to: humbertofoyacasibat@gmail.com

1 Department of Neurology, Faculty of Health Sciences, Nelson Mandela Academic Hospital, Walter Sisulu University, Mthatha, South Africa

2 Epilepsy and Neurocysticercosis Clinic, Mthatha, Eastern Cape Province, South Africa
