*2.5.2. Analysis of quantitative trait loci*

A quantitative trait loci (QTL) refers to the trait that varies in degree and can be attributed to the interactions between two or more genes and their environment. Possible QTLs have been identified through microarray studies for alcohol uptake. An analysis is done across inbred mouse strains identified a group of genes for alcohol preference QTL on chromosome 9. These genes include *Arhgef12*, *Carm1*, *Cryab (heat shock protein)*, *Cox5a*, *Dlat*, *Fxyd6*, *Limd1*, *Nicn1*, *Nmnat3*, *Pknox2*, *Rbp1*, *Sc5d*, *Scn4b*, *Tcf12*, *Vps11* and *Zfp291* [65].
