**2.2. Experimental setup and procedure**

Sixty-eight participants (12 females and 56 males) aged between 20 and of 29 years were recruited from one university in Taiwan for IA experiment. None of the participants had bipolar or related disorders, depressive disorders, anxiety disorders, or agoraphobia. Participants were randomly divided into two groups, group 1: the emotional picture trial group, 34 participants (6 females and 28 males) aged between 19 and 25 years, and group 2: the emotional film trial group, 34 participants (6 females and 28 males) aged between 19 and 27 years. All participants filled out the CIAS, and were divided into the HIA group (n = 15 of group 1, n = 19 of group 2) or the LIA group (n = 19 of group 1, n = 15 of group 2). This study was approved by the Institutional Review Board of the National Taiwan University Hospital Hsinchu Branch (Hsinchu, Taiwan) under the research Project Number 100IRB-32.

Fifty participants (14 females and 36 males) aged between 20 and 36 years were recruited from two universities in Taiwan for IGD experiment. The participants were divided into IGD & HIA group (n = 19, 4 females and 15 males, aged between 20 and 36) and non-IGD & LIA group (n = 21, 9 females and 12 males, aged between 20 and 28) using both CIAS and DSM-5 criteria. This study was approved by Research Ethics Committee for Human Subject Protection of National Chiao Tung University (Hsinchu, Taiwan) under the Project Number NCTU-REC-102-009.

The experimental procedure consisted of three phases. First, in phase 0, participants were seated in a comfortable chair and introduced to the experimental purpose and procedure, and then signed an informed consent form. Second, in phase 1, the physiological baseline including respiratory signals (TAM), ECG signals, and facial images of participants was measured and recorded [54]. Third, in phase 2, emotional induction experiment was conducted, and participants were elicited by emotional induction materials [50, 51]. All physiological signals during the whole experimental period were acquired and recorded. These data acquired during the psychophysiological signal baseline was the stage of before emotional induction, and during the recording of the emotional induction was the stage of after emotional induction.
