5.1. Personal vulnerability factors

The factors of the model are dopaminergic dysfunction, reduced available processing resources, autonomic hyperactivity, and schizotypal personality traits. The dopaminergic dysfunction will reduce the activation of processing resources and affect tonic autonomic hyper activation. The interaction of the personal vulnerability factors and personal protectors leads the vulnerable individual to develop prodromal symptoms of drug use. However, the personal vulnerability factors are associated between the inherited genetic factors and/or early biological factors [28]. These factors have been thought to contribute to vulnerability to congenitally compromise brain structure and function.

Therefore, nurse should be aware with the assessment about biological factors such as genetic drug use to design nursing intervention.
