**7.4.3 Chondrogenesis with PBPC and HA**

Findings from second-look arthroscopy presented in the above 5 case series confirmed that it was possible to replicate the results of our animal model (Saw et al, 2009) in the human knee joint using a combination of postoperative intraarticular injections of autologous PBPC with HA after arthroscopic subchondral drilling. This method uses marrow stimulation to create an autologous scaffold that is subsequently seeded with both intraarticular injections of autologous PBPC and in-situ progenitor cells from the underlying marrow (Fig 24).
