**Meet the editor**

Tülay Aşkin Çelik is an associate professor with a Doctor of Biology degree from the Department of Faculty of Science and Art, Adnan Menderes University. She received her master degree in Biology from the University of Fırat, Elazığ, Turkey. She also completed her PhD degree in Biology from the University of Fırat in 1997. She is a member of the European Association for Cancer Research

(EACR) and Molecular Cancer Research Association (MOKAD). Currently, her scientific interests are bioactive phytochemicals and plant extracts on their functional role in cancer cells and *in vitro/in vivo* biological activities. Furthermore, she is also investigating the genotoxic and cytotoxic effects of medicinal plant extracts and environmental pollutants and pesticides.

Contents

**Preface VII**

**Section 1 Introductory Chapter 1**

Tülay Aşkin Çelik

**Section 2 Cytotoxicity of Chemicals 7**

and Takemi Otsuki

Joanna Kurek

Omid Gholami

**against Cancer 65**

**Conventional Treatments 21**

**Section 3 Cytotoxic Effects of Natural Substance 43**

Chapter 1 **Introductory Chapter: Cytotoxicity 3**

Chapter 2 **Cytotoxicity Caused by Asbestos Fibers and Acquisition of**

Chapter 3 **The Cytotoxic, Antimicrobial and Anticancer Properties of the**

Chapter 4 **Cytotoxic Colchicine Alkaloids: From Plants to Drugs 45**

Chapter 5 **Natural Products as Cytotoxic Agents in Chemotherapy**

Mouse, Mouna Khouchani and Abdeslam Jaafari

Chapter 6 **Cytotoxicity and Apoptosis Induction by Coumarins in CLL 89**

**Resistance by Continuous Exposure in Human T Cells 9** Hidenori Matsuzaki, Suni Lee, Naoko Kumagai-Takei, Yu Min, Nagisa Sada, Kei Yoshitome, Yasumitsu Nishimura, Megumi Maeda

**Antimicrobial Peptide Nisin Z Alone and in Combination with**

Angélique Lewies, Lissinda H. Du Plessis and Johannes F. Wentzel

Abdelmajid Zyad, Inass Leouifoudi, Mounir Tilaoui, Hassan Ait
