**27. Anti-aggregant treatment**

As aspirin is given at the classic anti-aggregant dose (75-100 mg) following classic anti-aggregant dose loading (150-300 mg) in adult MI cases, in Paediatric cases loading is given of 5 mg/kg/day followed by 3-5 mg/kg/day aspirin. Adolescents can benefit from doses similar to those of adults.

The administration of clopidogrel together with aspirin increases the chance of success. The recommended Paediatric dose for clopidogrel is 0.2 mg/kg/day [89]. In adult patients diagnosed with MI, after 300 mg loading, maintenance treatment is given of 75 mg/day clopidogrel. It is recommended that clopidogrel and aspirin treatment is continued for 12 months in adult patients after MI [23].

#### **27.1. Beta blockers**

When arrythmia has been determined in MI patients, electrolyte levels must be examined and if the electrolyte levels are normal, beta blockers are preferred in treatment. Metoprolol can be given for this at a single dose of 1-2 mg/kg/day [23]. In addition to the anti-arrhythmic effects of beta blockers, patients who have undergone MI also beenfit from the anti-ischaemic effect because of the vasodilatory properties.
