**Hearing Loss at High Frequencies and Oxidative Stress: A New Paradigm for Different Etiologies** Hearing Loss at High Frequencies and Oxidative Stress:

DOI: 10.5772/intechopen.76325

Klinger Vagner Teixeira da Costa, Kelly Cristina Lira de Andrade, Maria Eduarda di Cavalcanti, Ana Claudia Figueiredo Frizzo, Aline Tenório Lins Carnaúba and Pedro de Lemos Menezes Klinger Vagner Teixeira da Costa, Kelly Cristina Lira de Andrade, Maria Eduarda di Cavalcanti, Ana Claudia Figueiredo Frizzo, Aline Tenório Lins Carnaúba and Pedro de Lemos Menezes

Additional information is available at the end of the chapter Additional information is available at the end of the chapter

A New Paradigm for Different Etiologies

http://dx.doi.org/10.5772/intechopen.76325

#### Abstract

The clinical assessment of hearing loss has been transformed and revised in terms of interpreting the characteristics of patterns found in relation to the relative frequency of certain diseases. However, increasing the threshold to 4 kHz as a starting point for hearing loss has shown to be common to different diseases such as noise-induced hearing loss. In noise-induced hearing loss, for example, six mechanisms can be considered: conversion of sound pressure level into hearing level, vascular failure in the cochlear region responsible for hearing at 4 kHz, sound wave propagation velocity is very high and causes the displacement amplitude in the cochlear duct, the structure anatomy of the cochlea causes a collision of fluids in the first curve of the cochlea, characteristics of auricular pavilion resonance and external auditory canal, and sound attenuation of the acoustic reflex. It is hoped that this new paradigm for the different hearing losses will result in a different approach to the physiological changes that affect the auditory system in the form of high-frequency hearing loss. As such, preventing, treating, and avoiding exacerbations are possibilities to be investigated in order to guarantee efficient communication and quality of life for individuals.

Keywords: hearing loss, noise-induced hearing loss, oxidative stress, presbycusis, chronic kidney disease

© 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons © 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and eproduction in any medium, provided the original work is properly cited.
