**4. Conclusions**

Successful malaria elimination in the APMEN member States will greatly enhance the global drive to eliminate malaria. Malaria transmission in these States is complex. APMEN member States include the largest populations living in areas of malaria transmission risk outside Africa. They are a global source of ACT resistance, highest burden of *P. vivax* and zoonotic malaria, and face many geopolitical and socioeconomic factors that will challenge malaria elimination efforts. These challenges can be addressed in part through operational research to identify country specific solutions, making better use of operational data such as through implementing SDSS approaches, and strengthening surveillance and cross-border collaborations.
