**Meet the editors**

Sylvie Manguin is a full Research Professor at the UMR-HSM, Institute of Research for Development (IRD), based at the University of Montpellier, France. She is a leading medical entomologist, academician and researcher whose main interest concerns mosquitoes and vector-borne diseases such as malaria and dengue. With strong collaborations in the South, she has developed research studies

on *Anopheles* mosquitoes from three continents (Asia, Africa and Americas) in the fields of molecular species identification, population genetics, phylogenetics, vectorial capacities, spatial surveillance, midgut microbiota biodiversity, salivary immunological markers and vector control approaches. She is teaching medical entomology at the University of Montpellier (UM, France), Kasetsart University (KU, Thailand) and Gadjah Mada University (UGM, Indonesia). She is the author of more than 90 indexed publications, 6 book chapters and 3 books including "*Anopheles Mosquitoes: New Insights into Malaria Vectors*" for which she is the editor (InTechOpen Access) and "*Biodiversity of Malaria in the World*" (John Libbey Ed.), respectively, published in 2013 and 2008. She is also the secretary-general of the International Federation of Tropical Medicine (IFTM), http:// www.iftm-hp.org/board.html, a member of the editorial boards of the Malaria Journal and Acta Tropica, and serves as reviewer in several international institutions and in more than 20 scientific journals. In 2018, she has been appointed by the National Agency for Sanitary Security of Food, Environment and Work (ANSES, France) as an expert in the working group on 'Vectors'.

Vas Dev has superannuated from the National Institute of Malaria Research, New Delhi - a premier Indian research organization for malaria research, and served as Officer-in-Charge of one of its Field Stations based in Assam, north-eastern region of India, for over 25 years. He was actively involved in operational research for evaluation of newer technologies for vector control, routine surveillance of

antimalarial medicines for treatment, diagnostics and human resource development. His primary research interests are in vector biology with special reference to epidemiology and control of malaria and other vector-borne diseases. His research efforts have culminated in number of technologies, viz., long-lasting insecticidal nets for vector control, artemisinin-based combination therapy for treatment of drug-resistant malaria, rapid diagnostic test kits that all have been incorporated for benefit of state healthcare services of north-eastern states, major public and private sectors and defence establishments alike resulting in substantial disease transmission reduction. He has over 150 research publications in peer-reviewed journals and is a serving member of the editorial board of many scientific periodicals. Dr. Dev is recipient of several coveted fellowships, awards and distinctions in his field of research, and is currently an active member of learned societies.

Contents

**Preface IX**

**Section 2 Major Challenges 13**

Umberto D'Alessandro

**Next Pandemic in Africa 41**

**vivax Malaria 77**

Chapter 1 **Malaria Elimination: Challenges and Opportunities 3**

Chapter 2 **The Artemisinin Resistance in Southeast Asia: An Imminent Global Threat to Malaria Elimination 15** Aung Pyae Phyo and François Nosten

Chapter 3 **Preparing for the Next Global Threat: A Call for Targeted,**

Chapter 4 **Challenges in the Control and Elimination of Plasmodium**

Puji BS Asih, Din Syafruddin and John Kevin Baird

**and Challenges for Elimination 95**

Chapter 5 **Human and Simian Malaria in the Greater Mekong Subregion**

Jeffrey Hii, Indra Vythilingam and Arantxa Roca-Feltrer

Chris Drakeley, Bronner Gonçalves, Lucy Okell and Hannah Slater

Chapter 6 **Understanding the Importance of Asymptomatic and Low-Density Infections for Malaria Elimination 129**

Colin Ohrt, Thang Duc Ngo and Thieu Quang Nguyen

**Immediate Decisive Action in Southeast Asia to Prevent the**

**Section 1 Introduction 1**
