*4.6.1. Partial syndactyly of the second and third toe*

Syndactyly is one of the most common congenital limb malformations involving the fusion of two or more fingers due to the failure of separation process during the development of limbs in the first trimester. In the lower limbs, the most common location is between the second and the third finger [75].

It is a heterogeneous clinical phenotype, as it may be: unilateral or bilateral, symmetrical or asymmetrical, partial or complete, cutaneous or bony, involving only the phalanges and/ or metatarsal bone, or may extend to tarsal bones or even the calf bones.

Partial syndactyly of the second and third toe may appear as a clinically isolated phenotype (the most common is zygodactyly) [75] or may be associated with syndromes such as:


Partial syndactyly of the second and third toe does not affect the motor function, and therefore does not require correction.
