**6.2. Omphalocele**

In contrast to gastroschisis, there is a low risk of fluid and health losses in neonates with omphalocele, but still a coverage with saline-soaked gauze is required. Postnatal outcome and surgical management depends on the associated anomalies, such as congenital heart disease and pulmonary hypoplasia. Also, fetal gestational age and the size of the defect are relevant [18]. In cases of a small AWD, primary closure is the preferred therapeutic procedure, while in cases of a larger defect, multiple surgeries may be required to repair the considerable defect. Various agents such as povidone-iodine, sulfadiazine, neomycin, silver-impregnated dressings, neomycin, polymyxin and bacitracin ointments have been reported to help with the formation of an eschar of the amnion sac. There are different surgical techniques for the cure of omphalocele that include serial reductions or closing the defect gradually after replacing the sac with a mesh [24].
