*4.1.2.5. Ocimum oil (basil)*

Orafidiya et al. performed two studies regarding the potential use of ocimum oil derived from the leaves of *Ocimum basilicum* L. in wound healing applications [97]. First, they studied its potential effect on the healing of full-thickness excisional and incisional wounds in an animal model [97]. They found and improved wound healing performance in wounds treated with the essential oil in comparison with the control [97]. In the second study, Orafidiya et al. demonstrated a significant antiseptic effect of a 2% solution of ocimum oil against strains and isolates from boils, wounds and acne [98]. This group was not the only one testing the potential effect of basil extract. Another similar study was performed by Singh and Majumdar, who studied the potential anti-inflammatory action of ocimum oil. They found a significant inhibition of vascular permeability and leucocyte migration in animal studies [99]. Singh conducted another study, in which he determined that the anti-inflammatory activity of ocimum oil could be related to a blockading of the enzymes cyclooxygenase and lipoxygenase in the arachidonic acid metabolism [100].
