**Preface XI**


#### Chapter 2 **Aggregation of Cyclodextrins: Fundamental Issues and Applications 45**

Tânia F.G.G. Cova, Sandra M.A. Cruz, Artur J.M. Valente, Paulo E. Abreu, Jorge M.C. Marques and Alberto A.C.C. Pais

#### **Section 2 Applications of Cyclodextrins 67**

Chapter 3 **Interactions between Bio-Based Compounds and Cyclodextrins 69**

> Bruno Filipe Figueiras Medronho, Sandra Gonçalves, Raquel Rodríguez-Solana, Artur J.M. Valente and Anabela Romano



Preface

that is, α-CD, β-CD, and γ-CD.

in research with cyclodextrins.

for bringing out the book in the present form.

The history of cyclodextrins (CDs) began in France in the late nineteenth century, and they were obtained from the enzymatic degradation of one of the most essential polysaccharides, starch. Their remarkable inclusion complexation properties led to a "host-guest"-type rela‐ tionship, thus modifying or improving the physicochemical properties and/or bioavailabili‐ ty characteristics of the guest molecules. Negligible cytotoxic effects enabled scientists and researchers to explore their applications ranging from pharmaceutical to biotechnology in‐ dustries. Further expansion of their application in the different field of cosmetics, food, agri‐ culture, textile, separation process, analytical methods, catalysis, environment protection, and diagnostics was made possible by the production of the three CDs known as "native,"

The book *Cyclodextrin - A Versatile Ingredient* is the result of collective work that addresses, in a clear and comprehensive way for readers, the fundamental aspects of CDs as well as their applications. Twelve chapters have been placed under two heads. The first section deals with the overview of the properties of cyclodextrins along with primary issues related to aggregation, whereas specific applications in various fields are covered in the second sec‐ tion, for further advancement in the physical sciences. Efforts have been made to provide an invaluable resource and pedagogical support for academician in general and researchers in specific as well as for industrial scientists with the introduction of the latest ongoing trends

The Editors are thankful to all the contributors of this book for their cooperation. My special thanks go to Ms. Marina Dusevic, Publishing Process Manager, and InTechOpen Publishing

**Dr. Poonam Arora (MPharm, PhD)**

**Dr. Neelima Dhingra (MPharm, PhD)**

Panjab University, Chandigarh

University Institute of Pharmaceutical Sciences University Institute of Pharmaceutical Sciences

GHG Khalsa Colleges Gurusar Sadhar, Ludhiana

India

India

