**6.2. Nuclear magnetic resonance**

Nuclear magnetic resonance (NMR) is mostly used to study inclusion complexation in solution and has been very useful in understanding the bonding configuration of functionalities present. This is mostly because when a guest is hosted the interior hydrogens are shielded by the guest resulting in a shift on the NMR spectroscopy [110]. NMR can also be used to determine the atoms that stabilize host-guest complexes using <sup>13</sup>C-NMR by monitoring the shifts of the carbon atoms involved [110, 115]. Furthermore, NMR can also provide information on the orientation of the guest within the host's cavity [115, 116].
