**Meet the editor**

Dr. Ahmed Lasfar is a member of the Cancer Institute of New Jersey, a principal investigator and a faculty member at Ernest Mario School of Pharmacy, Rutgers University, New Jersey. Dr. Lasfar is an innovator and a scientific adviser for pharmaceutical industry. He is an editor, a board member, and a reviewer of several international journals. He is often invited as a speaker for conferences

on cancer, immunology and pharmaceuticals. He graduated in France from Paris Rene Descartes University on medical and applied science. He completed his doctoral studies in Immunology at Paris Diderot University and his postdoctoral training in cancer immunology at Robert Wood Johnson Medical School, New Jersey. His research interests involve hematological malignancies, breast cancer, liver cancer and melanoma. His laboratory is more focused on cancer immunology and the elucidation of the mechanisms of cancer metastasis. He published breakthrough articles and holds patents for developing new drugs in oncology and infectious diseases.

Contents

**Preface VII**

Ahmed Lasfar

**Section 2 Pathogenicity and Diagnostic 7**

Tatsuaki Tsuruyama

Sadowska

**Section 1 Myeloid Leukemia: Multifaceted Disease 1**

Chapter 1 **Introductory Chapter: Myeloid Leukemia 3**

Chapter 4 **Proteomics in Acute Myeloid Leukemia 43** Chenyue W. Hu and Amina A. Qutub

**Section 3 Genetic and Epigenetic Regulations 63**

Chapter 5 **Genomics of Acute Myeloid Leukemia 65**

**Epigenetic Mechanism 105**

Oxana V. Klimenko

Lei Dong and Yu Zhu

Chapter 6 **Small Non-Coding RNAs in Regulation of Course and**

Chapter 2 **Cytopathology of MDS/MPN and AML by H&E Staining 9**

Chapter 3 **Acute Myeloid Leukemia in Pediatric Patients: A Review About Current Diagnostic and Treatment Approaches 21** Katarzyna Derwich, Dorothy Mitkowski and Jolanta Skalska-

Zeeshan Ansar Ahmed, Imran Ahmed Siddqui and Sadia Sultan

**Therapeutic Efficacy in Acute Myeloid Leukemia 85**

Chapter 7 **HIF-Regulated Leukemogenesis Through the Advances on**
