4. Conclusions

Salivary diagnostics is a promising field for the implementation of PoC technology. The desire for PoC, the potential of saliva, development of validated panel of salivary biomarkers for specific diseases and development of novel advanced techniques enables the application of saliva for the early detection and diagnosis of several oral and systemic diseases in a noninvasive, easy and fast personalized way. The recent technology advances, including liquid biopsy, EFIRM, biosensors, smartphones, microfluidics, paper-based technology, have the potential to make clinical utilities of saliva a reality in the near future. Saliva is predicted to be a substitute for blood, collected non-invasively for the diagnosis of oral and systemic diseases as well as chairside screening.
