**Meet the editor**

Dr. Janko Samardzic is an Assistant Professor and Clinical Pharmacologist at the Medical Faculty of the University of Belgrade in Serbia. He holds a PhD in Medical Pharmacology and has an extensive experience and expertise in Basic and Applied Neuroscience. Dr. Samardzic completed his postdoctoral studies at the University KU Leuven, Belgium and postgraduate courses

at the Erasmus University Medical Center in Rotterdam, the Netherlands. He also holds the position of Visiting Fellow at the University Children's Hospital Basel, Switzerland. Dr. Samardzic is a member of the European College of Neuropsychopharmacology, Austrian Pharmacological Society, Swiss Society of Clinical Pharmacology and Toxicology, and Serbian Pharmacological Society. He is the author of many peer-reviewed papers and a frequent speaker at international scientific conferences.

Contents

**Preface VII**

Chapter 1 **Introductory Chapter: GABA/Glutamate Balance: A Key for**

Chapter 2 **Early Life Experience, Maternal Separation, and Involvement of**

Chapter 3 **Notch Signaling in the Astroglial Phenotype: Relevance to**

Chapter 4 **Pharmacological Studies with Specific Agonist and Antagonist**

Chapter 5 **GABA and Glutamate: Their Transmitter Role in the CNS and**

Chapter 6 **Antagonists of Ionotropic Receptors for the Inhibitory**

Chapter 7 **Clinical Application of MR Spectroscopy in Identifying**

Tina Hinton and Graham A. R. Johnston

and Sunitha Palasamudram Kumaran

Christiane S. Hampe, Hiroshi Mitoma and Mario Manto

**Neurotransmitter GABA: Therapeutic Indications 91**

**Biochemical Composition of the Intracranial Pathologies 107** B C Hamsini, Bhavana Nagabhushana Reddy, Sankar Neelakantan

Janko Samardzic, Dragana Jadzic, Boris Hencic, Jasna Jancic and

López-Bayghen Esther, Angulo-Rojo Carla, López-Bayghen Bruno, Hernández-Melchor Dinorah, Ramírez Leticia and Ortega Arturo

**of Animal iGluR on Root Growth in Arabidopsis thaliana 47**

**Normal Brain Functioning 1**

**GABA and Glutamate Transporters 9**

**Glutamatergic Transmission 25**

Shashi Kant Singh and Ing-Feng Chang

Dubravka Svob Strac

Gabriela Beatriz Acosta

**Pancreatic Islets 65**
