**7. Conclusion**

Trauma represents a considerable and increasing demand on healthcare resources. Early resuscitation and on-arrival block forms primary goal initial management of polytrauma patients. Advances in regional anesthesia, better training and availability of point of care sonography allowed safer administration of RA and peripheral nerve block in critically ill polytrauma patients. Early administration of peripheral nerve blocks minimizes pulmonary and cardiovascular complications, decreases incidence of posttraumatic stress disorder and chronic pain syndrome, allows prompt mobilization and significantly reduces consumption of narcotic analgesics. Careful use of regional anesthetics in polytrauma patients, reduce duration of hospital stay and delirium in elderly patients. Regional anesthesia and peripheral nerve blocks are not devoid of adverse effects like systemic LA toxicity, neurovascular injury, and compartment syndrome. Selecting proper regional anesthesia technique, usage of appropriate local anesthetic concentration and volume, these complications can be reduced. RA is more versatile and reliable than ever before, with appropriate patient selection and usage of ultrasonography, such interventions are effective and safe. When used carefully in selected polytrauma patients regional anesthesia provides a cost-effective and safer method of analgesia in injured patients in both during surgery and perioperative settings.
