Acknowledgements

This work received financial support from FCT, Fundação para a Ciência e Tecnologia) through project UID/QUI/50006/2013–POCI/01/0145/FEDER/007265 with financial support from FCT/MEC through national funds and co-financed by FEDER, under the Partnership Agreement PT2020. PhD grant [SFRH/BD//2009] supported by FCT. Authors would like to thank Professors Silvia M. Arribas and Maria Carmen González from Department of Physiology, School of Medicine, University Autónoma de Madrid, Spain, for their assistance in the use of the Confocal Microscopy.
