**3.1. Neutrophils**

The most important effect of GCs on neutrophils is the inhibition of neutrophil adhesion to endothelial cells. This effect reduces trapping of neutrophils in the inflamed region and probably is responsible for the characteristic hematological change—neutrophilia. GCs at pharmacologic doses, only modestly impair neutrophil functions, such as lysosomal enzyme release, the respiratory burst, and chemotaxis to the inflamed region. Lower doses do not affect these functions [26, 27].
