**1. Introduction**

80 Fungicides for Plant and Animal Diseases

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Currently, the consequences derived from application of fungicides in traditional agricultural production systems for control of crop diseases have impacted negatively this activity. Fungicides application, where the indiscriminate use and application frequency high has led to problems and constraints in the control of these diseases by loss in efficiency, increased resistance to active ingredients, ecological damage and a serious negative impact on the human health. For this reason, it is had carryed out research to develop new products, methods and strategies for diseases control. The investigation and development of bio-based products is of great interest to subtract the negative effects generated by traditional agricultural production systems. The use and application of bioactive phytochemicals with antifungal properties represent an attractive and efficient alternative to inhibit the growth of several fungal pathogens.

These bioactive compounds are naturally produced in the plants how secondary metabolites, the principal groups with antifungal activity were terpenes, tannins, flavonoids, essential oil, alkaloids, lecithin and polypeptides. These groups of compounds are important for the physiology of plants contributing properties confer resistance against microorganisms, other organisms and help preserve the integrity of the plant with continuous exposure to environmental stressors, such as ultraviolet radiation, high temperatures or dehydration.
