**Meet the editor**

Dr.Ranjith Kumavath's Laboratory focuses on cutting-edge drug delivery systems to tackle the challenges with various types of cancers and infectious diseases. At present the lab is engaged in the discovery of bioactive compounds and peptides, like PMAP-18, SlpAs, carotenoid pigments, cardiac glycosides, etc., which are found in a host's immune system and membrane-action

to understand the altered pathways. Gene expression mechanism of CY-P19A1 in breast cancer by Rbn and Rdn for therapeutic biomarkers. Ranjith Kumavath's group is also working on the functional sequence-specific antibiotic resistance genes underlying the Two Component Signal Transduction TCST mechanisms to make sense of the deluge of transcriptomics and metagenomics data by identifying the specifics of sequence-encoded molecular functions. Ranjith Kumavath has published many research publications, e.g., *Nature Scientific Reports* and *System Biology*, among others.

Contents

**Preface VII**

**Section 1 Antimicrobial Resistance 1**

**Microbiome 3**

**Section 2 Metagenomic Applications 17**

**Migratory Birds 35**

**Section 3 Infectious Diseases 53**

**Human Viral Infections 19**

Chapter 1 **Metagenomics of Antimicrobial Resistance in Gut**

Madangchanok Imchen and Ranjith Kumavath

Chapter 2 **Potential Applications and Challenges of Metagenomics in**

Chapter 4 **Metagenomic Approaches for Investigating the Role of the**

Chapter 5 **The Microbiome of Spodoptera littoralis: Development, Control**

Tilottama Mazumdar, Beng-Soon Teh and Wilhelm Boland

Le Loir, Gwénaël Jan and Vasco Azevedo

**and Adaptation to the Insect Host 77**

**Microbiome in Gut Health and Inflammatory Diseases 55** Rodrigo Carvalho, Fillipe Carmo, Sara Heloisa, Barbara Cordeiro, Aline Vaz, Enrico Gimenez, Luis Goulart, Aristóteles Góes-Neto, Yves

Prudhvi Lal Bhukya and Renuka Nawadkar

Chapter 3 **Public Health Implications of Intestinal Microbiota in**

Takehiko Kenzaka and Katsuji Tani
