**3. The correlation between area ratios and the histological characteristic of cerebral vessels of newborn cadavers**

Despite the progression of atherosclerosis with aging being widely studied, there are limited studies in newborns. Many studies evaluated the diameters of peripheral vessels in adults, but only few studies were conducted on CCA and its branches in newborns [3, 6, 12, 19, 22]. Thus, an early beginning of atherosclerosis is suggested to initiate in the early period of life. Then, the purposefulness was to scrutinize the anatomical and histological characteristics of cerebral vessels in newborn cadavers. Consequently, it has been hypothesized that variations in carotid bifurcation lumen geometry would be the self-regulating prognosticators of ICA atherosclerosis, aiming to reveal the early beginning of atherosclerosis in newborn cadavers. The relation between the endothelial destruction and the outflow to inflow area ratio was also been inspected in some studies.
