P < 0.05.

##P < 0.01.

###P < 0.001 versus 20 weeks (paired sample t-test, n = 10).

\*\*\*P < 0.001 versus normal diet (independent sample t-test, n = 10).

**Table 1.** Serum lipid values and body weight in cholesterol-fed rabbits (baseline, 20 weeks of cholesterol) followed by dietary lipid lowering for 4 weeks (normal diet) or a restricted diet for 4 weeks (restricted diet).

Despite increased levels of circulating LDL, there is no difference in lipid accumulation in the liver or aorta of rabbits undergoing severe food restriction. Both normal diet and food restriction do not affect serum triglycerides (**Table 1**).
