**Low-Carbohydrate High-Fat (LCHF) Diet: Evidence of Its Benefits Benefits**

**Low-Carbohydrate High-Fat (LCHF) Diet: Evidence of Its** 

DOI: 10.5772/intechopen.73138

Parijat De and Sagnik Mukhopadhyay

[17] Akanji MA, Yakubu MT. α-Tocopherol protects against metabisulphate-induced tissue damage in rats. Nigerian Journal of Biochemistry and Molecular Biology. 2000;15(2):179-183

[18] Holman RR. Type 2 diabetes mellitus in 2012: Optimal management of type 2 diabetes

[19] Etuk EU. A review of medicinal plant with hypotensive or anti- hypertensive effect.

[20] Grover JK, Yadav S, Vats V. Medicinal plants of India with anti-diabetic potential. Journal

[21] Shanmugasundaram KR, Panneerselvam SP, Shanmugasundaram ER. Enzyme changes and glucose utilization in diabetic rabbit: The effect of Gymnema sylvestrae, R. Br. Journal

[22] Begum N, Shanmugasudnaram KR. Tissue phosphates in experimental diabetes, Arogya.

[23] Ekpenyong C, EAkpan EE, Udoh NS. Phytochemistry and toxicity studies of Telfairia occidentalis Aqueous Leaves Extract on Liver Biochemical Indices in Wistar Rats. Department of Physiology, College of Health Sciences, University of Uyo, Akwa Ibom State,

[25] Ghosh S, Suryawansi SA. Effect of Vinca roseaextracts in treatment of alloxan diabetes in

[26] Abolaji AO, Adebayo AH, Odesanmi OS. Effect of ethanolic extract of Parinari polyandra (Rosaceae) on serum lipid profile and some electrolytes in pregnant rabbits. Research

[27] Pari L, Uma M. Antihyperglysemic activity of Musa sapientum flowers: Effect on lipid peroxidation in alloxan-induced diabetic rats. Phytotherapy Research. 2000;14(2):136-138

[28] Virdi J, Sivakami S, Shahini S, Suthar A, Banavalikar MM, Biyani. Antihyperglycemic effects of three extracts from Momordica charantia. Journal of Ethnopharmacology. 2003;88(1):107-111

[29] Al-Shamaony L, Al-khazraji SM, Twaiji. Hypoglycaemic effect of Artemsia herba alba. Effect of a valuable etract on some blood parameters in diabetic animals. Journal of

[30] Rhoads GG, Gulbrandsen CL, Kagan A. Serum lipoproteins and coronary heart disease in a population study of Hawaii Japanese men. The New England Journal of Medicine.

[31] Mediene-Nenchekor S, Brosseau T, Richard F. Blood lipid concentrations and risk of

[32] Brewer HB. Hypertriglyceridemia: change in the plasma lipoproteins associated with an increased risk of cardiovascular disease. American Journal of Cardiology. 1999;83(9):3F-12F

[24] Tiez NW. Fundamentals of Clinical Chemistry. Philadelphia: WB Saunders; 1986

male albino rats. Indian Journal of Experimental Biology. 2001;39:748-759

mellitus remains elusive. Nature Reviews Endocrinology. 2013;9(2):67-68

Journal of Medical Sciences. 2006;6(6):894-900

of Ethnopharmacology. 2002;81:81-100

of Ethnopharmacology. 1983;7:205-216

Journal of Health Science. 1978;4:129-139

Journal of Medicinal Plant. 2007;1:121-127

Ethnopharmacology. 1994;43(3):167-171

myocardial infarction. The Lancet. 2001;358(9):1064-1065

1979;294(6):293-298

Nigeria; 2012. pp. 10-59

70 Diabetes Food Plan

Parijat De and Sagnik Mukhopadhyay Additional information is available at the end of the chapter

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/intechopen.73138

#### **Abstract**

Current dietary recommendations state that there is insufficient evidence to prescribe an exact percentage of calories from carbohydrate, protein and fat for people with diabetes from the choice of a variety of popular diets currently available. Over the years, many a research has focused on the relative importance of the right proportion of carbohydrates and fat combination in a balanced diabetic diet. Jury is still out regarding the relative merits and demerits of a diabetic diet – low carbohydrate, high fat or low fat, high carbohydrate diet. Evidence from various studies suggest that low carbohydrate diets improve cardiovascular (CVD) risk through lowering HbA1c levels, improving blood pressure and body weight. There is also a positive effect on lipid profile and reversal of non-alcoholic fatty liver disease (NAFLD). Whilst there are some significant metabolic benefits of LCHF diet, it is accepted that there needs to be more long-term studies before it can be used in daily clinical practice.This chapter focuses on basic physiology and metabolism of carbohydrate and fat content in normal and diabetic patients and a review of the literature on these two diet combinations with current thoughts and evidence on this core issue affecting insulin utilization and metabolic profile.

**Keywords:** carbohydrate, fat, diabetes, metabolic syndrome, insulin, insulin resistance, weight gain, lipids, NAFLD, cardiovascular disease
