**Acknowledgements**

The work was carried out in the RECETOX Research Infrastructure supported by the Czech Ministry of Education, Youth and Sports (LM2015051), and the European Structural and Investment Funds, Operational Programme Research, Development, Education (CZ. 02.1.01/0.0/0.0/16\_013/0001761). This work was supported also by the Slovak Research and Development Agency under the contract No. APVV-0450-17.
