**Acknowledgements**

We would like to thank Dr. Nadav Elad from the Electron Microscopy Unit, Departments of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel, for the great TEM analysis and to Victoria Reingold for the in situ immunofluorescence data of CGMMV. This work was supported by the Chief Scientist, Israel Ministry of Agriculture, and the Plant Production and Marketing Board for CGMMV initiative project number 132–1740 and *Tm-22* Tobamo breaker in tomato plants, initiative project number 261–1159.
