4.3. Neuron-related genes

A great number of genes that encode specific proteins for calcium, sodium and potassium pumps, synapsis and cell excitability show a major decrease in the first week following SCI [26]. This reduction reflects alterations of gene profile in neurons and the progress of apoptosis that occurs after SCI. Late axonal regeneration after SCIs is accompanied by overexpression of CORO1B (Coronin, actin binding protein, 1B), RAB13 (Rab13, member RAS oncogene family), NINJ (Ninjurin), ANK (Ankyrin), cAMP-related genes and myelin oligodendrocyte glycoprotein [27].
