**Mitochondria and Heart Disease**

**Mitochondria and Heart Disease**

Shaunrick Stoll, Christiana Leimena and Hongyu Qiu Shaunrick Stoll, Christiana Leimena and Hongyu Qiu Additional information is available at the end of the chapter

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/intechopen.72611

#### **Abstract**

Mitochondria play a key role in the normal functioning of the heart and in the pathogenesis and development of various types of heart disease. In addition, specific mitochondrial cardiomyopathies due to mutations in mitochondrial DNA have been identified. Increasing studies demonstrate that mitochondrial function has emerged as a therapeutic target in heart disease. This chapter addresses the recent studies of the role and the mechanism of mitochondria in the development of heart disease, and the progress in clinical diagnosis and treatments on a mitochondrial basis. Consequently, the aim of this chapter is to outline current knowledge about mitochondria in the heart disease.

DOI: 10.5772/intechopen.72611

**Keywords:** mitochondria, heart, heart failure, cardiac hypertrophy, heart disease
