**Meet the editors**

Eylem Taskin is a physiologist. She worked as a postdoctoral researcher at New York University for two years. She has published more than twenty articles and four international book chapters. She has also edited a book. She has worked on the editorial board for several scientific journals.

Celal Guven graduated from the Department of Biophysics, Istanbul University. He has been working on protein-chemical interactions. He has published almost ten articles and four international book chapters. He has also edited a book. Dr. Guven has worked on an editorial board for a national journal.

Yusuf Sevgiler graduated from the Department of Biology, Çukurova University. He has published twenty articles about oxidative and neurotoxic potentials of xenobiotics and reviewed many. Dr Sevgiler has also published two international book chapters and has edited a book as well.

Contents

**Preface IX**

Peter Kaplan

**Development 85**

**Normal Cells 87**

**Section 1 Mitochondrial Dysfunction and Cardiovascular Diseases 1**

Shaunrick Stoll, Christiana Leimena and Hongyu Qiu

Chapter 3 **Interplay Between Mitochondrial Proteins and Age-Associated**

Chapter 4 **Differential Effect of Atpenin A5 on ROS Production from Wild-Type Mitochondrial Complex II in Human Cancer Cells and**

Zuzana Tatarkova, Martin Kolisek, Ivana Pilchova, Peter Racay and

Fumiaki Uchiumi, Jun Arakawa, Yutaka Takihara, Motohiro Akui,

Chapter 1 **Mitochondria and Metabolism in Right Heart Failure 3**

Danielle R. Bruns and Lori A. Walker

**Risk of Cardiovascular Diseases 61**

**Section 2 Mitochondrial Dysfunction and Anticancer Drug**

Madhavi P. Paranagama and Kiyoshi Kita

**Function-Associated Genes 107**

Hiroshi Hamada and Sei-ichi Tanuma

Chapter 5 **A New Insight into the Development of Novel Anti-Cancer Drugs that Improve the Expression of Mitochondrial**

Chapter 2 **Mitochondria and Heart Disease 31**
