**Phenolic Compounds from the Natural Sources and Their Cytotoxicity Phenolic Compounds from the Natural Sources and Their Cytotoxicity**

Shagufta Perveen and Areej Mohammad Al-Taweel Areej Mohammad Al-Taweel

Additional information is available at the end of the chapter Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/66898

Shagufta Perveen and

### **Abstract**

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DOI: 10.1016/j.jhazmat.2008.12.115

28 Phenolic Compounds - Natural Sources, Importance and Applications

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Natural phenolic compounds are considered as one of the important secondary metabolites for their chemopreventive and chemotherapeutic effects in cancer. These compounds show potent activities for cancer prevention and its treatment. There are many phenolic compounds present in medicinal and edible plants such as, flavonoids, bioflavonoids, stilbenes, chalconoids, chromones, phenylpropanoids, curcuminoids, coumarins, tannins, lignans, neolignans, anthraquinones, quinones, xanthones, phenolic acids and their glycosides and many more. The antioxidant potential of phenolic compounds is almost bolded in the treatment and prevention of cancer. Mono phenolic, polyphenolic and phenolic acids compounds from a large variety of plants, foods, spices, insects, fungus, beverages, lichens, algae and mammals have been shown to inhibit or attenuate the initiation, progression and spread of cancers in cells in vitro and in animals in vivo. In this chapter, we try to cover general view and the recent literature to summarize structural information and cytotoxic effects of phenolic compounds on different cancer cell lines from medicinal herbs and plants.

**Keywords:** natural phenolic constituents, cytotoxic activities, cancer cell lines
