Contents

### **Preface XI**


Chapter 7 **The Role of Circulating Biomarkers in the Early Diagnosis of Ovarian Cancer 157** Ece Gumusoglu and Tuba Gunel


Preface

Our understanding of ovarian malignancy is constantly changing and over the last few years research into cancer genetics and molecular biology has revealed a huge amount of information. This knowledge has been used to develop management strategies as well as new and novel treatment agents. The role of clinical genetics to guide treatment protocols and preventative surgical options has also entered the clinical domain. The place of surgery, be it as a primary manoeuvre, or as an adjunct to primary chemotherapy as well as in the recurrent setting, is still being defined. This book brings together a variety of up-to-date con‐ cepts in the field of ovarian cancer management and addresses some of these issues. Special‐ ists from around the world have contributed a variety of topics, including pathogenesis, molecular biology, diagnosis, screening, and both surgical and chemotherapeutic manage‐ ment. In addition, newer novel treatment strategies have also been outlined. This book out‐ lines the breadth of scientific knowledge that forms the basis of new concepts in this disease and addresses the traditional treatment strategies. We hope the reader will be encouraged to explore this subject further and also contribute to the research of this devastating disease.

**Dr. Andreas Papadopoulos and Professor Omer Devaja**

Department of Gynaecological Oncology

Kent Oncology Centre, UK

