**9. Summary**

Chemotherapy is the first systemic treatment of epithelial ovarian cancer at all disease stages. It is based on platinum with paclitaxel in the adjuvant and neoadjuvant setting. In advanced stage cases chemotherapy with bevacizumab improved the response.

Most cases of newly diagnosed ovarian cancer will respond to initial therapy, but 80% or more will ultimately relapse and further chemotherapy may be indicated. Newer strategies involving gene testing such as BRCA has proven to be an important addition to the treatment strategy. The choice of treatment for recurrent disease is based on the duration of response to prior therapy, previous treatment toxicity and quality of life.
