*5.2.2. Metastases in regional lymph nodes: N*

In a recent meta-analysis including 14 studies and 5579 gastric cancer patients, high GPS was significantly associated with presence of lymph node metastases (OR 4.60; 95% CI = 3.23–6.56) as well as with lymphatic (OR 3.04; 95% CI = 2.00–4.62) invasion [106].
