**4. Conclusion**

BPA in daily life are considered safe; however, low-dose effects are observed in experimental studies. Early life exposure to low-dose BPA may increase the risk of developing adult onset of disease, and the biological changes can transmit to the third or fourth generation. Therefore, EFSA propose the tolerable daily intake levels of BPA from 50 to 4-ug/kg bw/day. Low-dose effects of BPA are ongoing controversy because of the inconsistent results. Epidemiologic evidences such as nested case control studies are needed to provide the human health effects caused by exposure to low dose of BPA.
