**1. Introduction**

Bisphenol A (BPA) is a monomer used in polymer plastic material and is used comprehensively in the manufacture of polycarbonate plastics and epoxy resins. More specifically, food packaging bottles are mostly made of polycarbonate plastics, though the resins are usually used for polishing and coating of metal products including food cans, bottle tops, and water supply pipes. BPA is also used in the manufacture of polyacrylate resins, polysulfone resins, polyester resins, flame retardants, and in the recycling of thermal paper. Dental sealants and

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polymeric tooth coatings also contain BPA [1]. We are exposed BPA toxicity directly through its products or indirectly throughout contaminated surroundings. Diet (food and beverages) is the chief source of human exposure to BPA, though air, dust, and water (including skin contact during bathing and swimming) are other possible sources of exposure. It was also noted that thermal printing paper (cashier's receipts) causes contamination of human skin with BPA. However, individuals employed in the BPA industry can be exposed directly to BPA at the workplace [2]. Leaching of BPA from polycarbonate products depends on the contact time, temperature, and type of food. It takes place either through the hydrolysis (breaking H+ and OH– ions) of residual BPA in polycarbonate products after they are developed or through diffusion in the case of dry food products. The presence of food simulators as 50% ethanol (C2 H5 OH) or 3% acetic acid (CH<sup>3</sup> COOH) also causes enhanced leaching of BPA in food [3]. BPA may be the bona fide endocrine disruptor that unfavorably affects metabolic homeostasis. Endocrine disrupting chemicals (EDCs) have the capability of hindering normal endocrine systems. The two EDCs, BPA and triclosan (TCS), are mass produced and widespread.
