5. Summary and discussion

In many fields, personalized medicine has already been successfully introduced. In spinal implant surgery, patient-specific implants with an optimized fit shape could minimize severe complications. Depending on the question of cause, it is also possible to disassemble the basis plate of the implant into even smaller subunits in order to be able to make more detailed statements. If necessary, a hybrid model consisting of MBS and FE parts can also be created. However, it is always important to consider how exact the model must be. The desired precision determines how many more parameters, whose biomechanical properties must be known, flow into the model. However, some of these biomechanical parameters can only be inadequately determined. Furthermore, the calculation time increases with the increase in the fine structure of the model.

The presented modeling should not be seen as a competition to the FE modeling because our aim is to pursue a holistic way of looking at patients. Therefore, detailed models should be implemented in a whole-body model to simulate dynamic everyday situations and to obtain patient-specific knowledge about the stress situation in the fine-structured area. A valid modeling is indispensable, which can be ensured by selecting suitable input parameters. Because personalized input parameters of the model are often difficult to determine, we try to develop a procedure for the determination of patient-specific biomechanical properties of the human structures, which also guarantees rapid availability of these data as input parameters for the modeling.
