**Comorbidities in Chronic Spontaneous Urticaria**

Müzeyyen Gönül, Havva Hilal Ayvaz and Selda Pelin Kartal

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/67911

#### **Abstract**

Chronic spontaneous urticaria (CSU) is a disease that makes people's lives miserable with unknown etiology. In recent years, there have been many studies trying to explain the etiology of CSU, and many of them reported that there are some comorbidities or triggering factors related to CSU. However, it has not been clearly known yet that whether these conditions are true comorbidities associated with CSU or they are coincidentally found at the same time. In this chapter, related comorbidities and conditions have been told.

**Keywords:** chronic spontaneous urticaria, autoimmunity, infectious diseases, psychological comorbidities, coagulation factors, metabolic syndrome

#### **1. Introduction**

Chronic spontaneous urticaria (CSU) is a common mast cell-driven skin disorder characterized by the occurrence of recurrent and spontaneously daily or frequent wheals with or without angioedema, for more than 6 weeks with symptoms present at least three times weekly [1, 2]. CSU affects 0.1–5% of the population, especially during the third and fourth decades and predominantly women [3]. There are many studies that some disorders or conditions may be related to CSU.
