Contents

#### **Preface XI**


Preface

genetic mechanism is better known.

epilepsy, and GAD and epilepsy.

before they were accepted for publication.

Psychogenic non-epileptic seizures (PNES) and epileptic seizures (ESs) are a very common health problem of human beings since their origin. ESs were considered as a sacred disease for thousands of years, while for the past hundred years, a real knowledge of its etiopatho‐

This book contains a group of selected peer-reviewed chapters that were revised by mem‐ bers of the IJN Editorial Board and the chief editor of this project at least twice. An impor‐ tant number of recommendations and modifications were implemented on the chapters

An overview of genetic testing modalities and workflows taking into account the genetic architecture of epilepsies is given, and the practical aspects of genetic testing in epilepsies,

This book aims to present in synthesized form the role of genetic, immunological, and envi‐ ronmental factors in autoimmune epilepsy and the treatment of PNES and ES as well. A review of the work achieved during the last years in patients with this condition provides information and experience on the diagnosis and treatment of these epilepsy types. This book reports results from a systematic search of PUBMED, looking for articles published about autoimmune epilepsy, autoantibodies and epilepsy, NMDA and epilepsy, AMPA and

Some authors estimated the prevalence of ischemic stroke in patients presenting subarach‐ noid neurocysticercosis and epileptic seizures, while others deliver their results from con‐ ducted interviews, literature reviews, expert panels, and online surveys to assess the availability and quality of patient-reported data during epilepsy diagnosis and treatment, respectively. Their results highlight important data collection and design opportunities to

Finally, we discuss about the treatment for pseudoseizures in a professional manner and the results of the study done on PNES in patients living in rural South Africa. Because NCC is the leading cause of epileptic seizures in developing countries where PNES is also a fre‐ quent problem, to distinguish real seizures from PNES is a challenge. Therefore, this book shows the updated information published in the medical literature and compares it with

The seven chapters in this book, authored by some of the world's top neurologists and re‐ searchers in the field of central nervous system, provide a valuable update on the topic of seizures, providing a timely review of the achievements in PNES and ES, covering historic aspects, genetics, pathogenesis, clinical aspects, and imagenology, among others. Contribu‐

the authors' results and highlights how to differentiate epileptic seizures from PNES.

including advantages/limitations and clinical utility of tests, are discussed.

support the diagnosis, treatment, and self-management of epilepsy.
