Contents

## **Preface XIII**


Chapter 7 **Hypoxia, Angiogenesis and Atherogenesis 113** Lamia Heikal and Gordon Ferns


**Section 5 Pro-angiogenic and Anti-angiogenic Therapies 341**

Chapter 8 **Coronary Collateral Growth: Clinical Perspectives and Recent**

Chapter 9 **Angiogenesis and Cardiovascular Diseases: The Emerging Role**

Chapter 10 **Unique Phenotypes of Endothelial Cells in Developing Arteries:**

Kathleen Graham, Liya Yin and William Chilian

Ana Moraga, Ka Hou Lao and Lingfang Zeng

**A Lesson from the Ductus Arteriosus 175** Norika Mengchia Liu and Susumu Minamisawa

Chapter 11 **Vascular Repair and Remodeling: A Review 195**

**Section 3 Mechanisms of Tumor Angiogenesis 213**

Chapter 12 **Tumor Angiogenesis: A Focus on the Role of**

Chapter 13 **VEGF-Mediated Signal Transduction in Tumor**

Chapter 14 **Noncoding RNAs in Lung Cancer Angiogenesis 251**

Tomuleasa and George Adrian Calin

**Section 4 Novel Methods in Angiogenesis Research 291**

Chapter 16 **Novel Methods to Study Angiogenesis Using Tissue**

**their Clinical Applications 293**

and Muhammad H. Hafeez

**Explants 319**

Lucia Napione, Maria Alvaro and Federico Bussolino

Chapter 15 **Recent Advances in Angiogenesis Assessment Methods and**

Tomoko Takahashi, Keiko Fujita and Masumi Akita

Ioana Berindan-Neagoe, Cornelia Braicu, Diana Gulei, Ciprian

Imran Shahid, Waleed H. AlMalki, Mohammed W. AlRabia,

Muhammad Ahmed, Mohammad T. Imam, Muhammed K. Saifullah

**Cancer Stem Cells 215** Keiko Fujita and Masumi Akita

**Angiogenesis 227**

Bhamini Patel, Peter Hopmann, Mansee Desai, Kanithra Sekaran,

Nicolás F. Renna, Rodrigo Garcia, Jesica Ramirez and Roberto M.

**Insights 133**

**VI** Contents

**of HDACs 149**

Miatello

