the differences within one group in comparison with the data obtained before 6 weeks.

•the differences within one group in comparison with data obtained at 7‐8 weeks (*#* < 0.05).

**Table 1.** Blood levels of pro‐ and antiangiogenic factors of the first trimester of pregnancy.


**\***Comparison with the control group;

**\*\***comparison with the main subgroup A;
