**4. Application of licorice products for pharmaceuticals and cosmetics**

Glycyrrhizin has also demonstrated antiviral, antimicrobial, anti‐inflammatory, antiallergy, antiulcer, antitussive, hepatoprotective, and blood pressure‐increasing effects *in vitro* and *in vivo*. In addition, glycyrrhizin is effective in treating hyperlipidemia and inflammation‐ induced skin hyperpigmentation and is effective in preventing neurodegenerative disorders and dental caries [2].

Therefore, licorice extract, glycyrrhizin, and its derivatives are extensively used in the prepa‐ ration of cosmetics in Japan. Glycyrrhizin as well as licorice extracts, glycyrrhetin, stearyl glycyrrhetinate, and succinyloxy ‐glycyrrhetinate (carbenoxolone) are used in drugs, quasi‐ drugs, and cosmetics. Glycyrrhizin and its salts are used in eye drops, lotions, and tonics as they are soluble in water. On the other hand, glycyrrhetic acid and its derivatives are used in creams, milky lotions, and sun oils as they are soluble in oil.
