**5. Conclusions**

Leukoaraiosis is a radiological finding whose pathogenesis or clinical significance is not completely acknowledged. LA predispose to stroke, independent of other stroke risk factors. Typically, leukoaraiosis predict a lacunar ischemic stroke but in patients with LA the risk of cortical infarct is also increased, as is that of vascular death. The presence of extensive LA predisposes to ICH, especially in patients treated with anticoagulants for secondary prevention after an ischemic stroke. Consequently, it is important for practicians to correctly assess LA in all patients presenting with cerebro-vascular pathology.
