**3. Conclusion**

The SIB-IMRT or SMART is feasible and time sparing with encouraging loco-regional results and controlled side effects. From a radiobiological point of view, it appears to be an effective RT strategy for the primary treatment of H&N cancers, and also for various other cancer types. Many different SIB schedules have been employed so far, but a standard regimen has not yet been defined. Based on the available published studies on the SIB-IMRT, the short-term clinical outcome is very promising. However, very few data on late effects are available as of yet, due to the short follow-up time in the majority of the reported studies. However, further data are awaited shortly from ongoing clinical trials in order to determine the most efficient protocol.

For the past 5 years, our department has been using the SIB method where it is applicable. All images shown in this chapter are actual images of patients we personally have treated.
