**2.1 Patients**

Fifteen patients were referred to the cytogenetic laboratory of the Brest University Hospital by medical geneticists, pediatricians and pediatric cardiologist for suspicion of WBS between 2002 and March 2011. The reasons for referral included cardiovascular anomalies, dysmorphism or a combination of signs suspecting WBS (Table 1). However, because of limited cell pellet available for one patient, the study could be performed only on 14 patients.
