**4. Conclusion**

Natural products are an extremely valuable source of novel compounds with potential analgesic properties. More research needs to be conducted on natural products to discover new compounds, and hereafter, new mechanisms of actions will be elucidated.

Lastly, the fields of pharmacognosy, medicinal chemistry and pharmacology are expected to work closely to ensure that novel naturally driven compounds are explored for their potential development as novel drugs as well as their pharmacological mechanisms of action.
