**8.1. The concept of LipoSpray**

Using the liposomal concept "LipoSpray" is an innovative idea in delivering an analge‐ sic in the form of liposomal suspension. The suspension is sprayed into the mouth and under the tongue. Liposomes penetrate the mucosal tissue of the mouth, and the drug is released from the liposome into the bloodstream, distributing the drug throughout the body in minutes.

This path bypasses the gastrointestinal (GI) track and bypasses the first‐pass effect of the liver. The analgesic in question would have a fast effect in pain management.

**Figure 15.** Various morphology of the polar and nonpolar arrangements in liposome and its formation.
