*Edited by Shymaa Enany and Laura E. Crotty Alexander*

<i>Staphylococcus</i> was first recognized as a human pathogen in 1880 and was named for its grape cluster-like appearance. In 1884, <i>Staphylococcus aureus</i> was identified and named for its vibrant golden color, which was later found to be the result of golden toxin production. Here, experts examine in-depth patterns of <i>S. aureus</i> colonization and exposures in humans, mammals, and birds that have led to the development of various clinical diseases. The mode of transmission of <i>S. aureus</i> and different methods for its detection in different samples are defined. Conventional antibiotic options to treat this aggressive, multifaceted, and readily adaptable pathogen are becoming limited. Alternative, novel chemotherapeutics to target <i>S. aureus</i> are discussed in the pages within, including herbal medicines, bee products, and modes of delivery.

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Frontiers in *Staphylococcus aureus*

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Frontiers in

*Staphylococcus aureus*

*Edited by Shymaa Enany* 

*and Laura E. Crotty Alexander*