**6. Conclusions**

The data in the literature suggest that OAEs represent a valid noninvasive instrument, which can monitor the cochlear damage entity in patients affected by MD, and could also monitor its progress. OAEs are not just reliable tools, but they are a low-cost methodology in comparison to standardized MD monitoring methods, such as electrocochleography.

The data in the literature shows that alterations in the inner ear caused by the presence of a hydrops can be monitored accurately with OAEs. Glycerol results can also be monitored successfully. Some reports suggest that a DPOAE protocol can be more suitable for MD monitoring tasks, but considering the mechanisms of OAE generation this might not be true. TEOAEs and DPOAEs can similarly detect inner ear alterations as long as these affect the basilar membrane mobility and the functioning of outer hair cells.

Although promising, this field of research still needs to be expanded, where experimental studies are lacking. It is likely that in the future, either implementing our knowledge among MD, or implementing the OAE technology, the application of the OAE for patients affected by MD could be further expanded and offered with more information to the clinical practice.
