**7.1 Demographics**

A total of eighty-eight (88) subjects (45 males and 43 females) gave informed consent. The subjects were divided into four test groups.

	- a. 5 subjects with point mutation in exon 4, codon 100, GAA to GGA, Glu to Gly) glu100gly;
	- b. 5 subjects with point mutation in exon 4, codon 113, ATT to ACT, Ile to Thr) ile113thr;
	- c. 5 subjects with point mutation in exon 5; codon 148, GTA to GGA, Val to Gly) val148gly;
	- d. 5 subjects with point mutation in exon 5, codon 148, GTA to GGA, Val to Ile) val148ile.

There was no statistically significant difference in age distribution between these groups, with a range of 16 to 73 years of age.
