**Meet the editor**

Martin H. Maurer graduated from medical school at the University of Heidelberg, Germany, and McGill University, Montréal, Canada, in 1999 – receiving his MD in 1999. As a post-doctoral fellow in 2003 at the Johns Hopkins University, Baltimore, Md., USA, he concentrated on neurological diseases and was appointed Assistant Professor of Physiology in 2005 and Associate Professor

of Physiology in 2007 at the University of Heidelberg. From 2007-08, he was a research group leader in the biotech industry. In 2009-10, he did clinical work in pediatrics, and since 2011 in child and adolescent psychiatry at the Mariaberg Hospital, Germany. His main research interests include neural stem cell differentiation, growth factors in the brain (EPO, VEGF, G-CSF), and neuropsychopharmacology.

Contents

**Preface XI** 

Chapter 1 **Amyotrophic Lateral Sclerosis:** 

Martin H. Maurer

Chapter 2 **Insights Arising from Gene** 

Chapter 4 *In Vivo* **and** *In Vitro* **Models to** 

Alessandro Vercelli

Chapter 6 **Electrophysiological Abnormalities in** 

Chapter 7 **Molecular and Electrical Abnormalities** 

Katharina A. Quinlan,

**Part 1 Pathophysiology and Methodology 1** 

**An Introduction to Treatment and Trials 3** 

Johnathan Cooper-Knock, Joanna J. Bury, Laura Ferraiuolo, Emily F. Goodall, Pamela J. Shaw and Janine Kirby

Chapter 3 **Dynamic Meta-Analysis as a Therapeutic** 

Cassie S. Mitchell and Robert H. Lee

**Study Amyotrophic Lateral Sclerosis 81**  François Berthod and François Gros-Louis

Marina Boido, Elisa Buschini, Antonio Piras,

**SOD1 Transgenic Models in Amyotrophic** 

Sherif M. Elbasiouny, Katharina A. Quinlan, Tahra L. Eissa and Charles J. Heckman

Sherif M. Elbasiouny and C.J. Heckman

**Expression Profiling in Amyotrophic Lateral Sclerosis 41** 

**Prediction Tool for Amyotrophic Lateral Sclerosis 59** 

Chapter 5 **Advantages and Pitfalls in Experimental Models Of ALS 125** 

Giada Spigolon, Valeria Valsecchi, Letizia Mazzini and

**Lateral Sclerosis: The Commonalities and Differences 157** 

**in the Mouse Model of Amyotrophic Lateral Sclerosis 175** 
