**How to Assess Disease's Severity and Monitor Patients with Amyotrophic Lateral Sclerosis: Lessons from Neurophysiology**

Ferdinando Sartucci1,2,3, Tommaso Bocci1,4, Lucia Briscese1, Chiara Pecori1,3, Chiara Rossi1 and Fabio Giannini4 *1Department of Neuroscience, Unit of Neurology, Pisa University Medical School, 2Institute of Neuroscience, CNR, Pisa, 3Department of Neuroscience, Unit Outpatients Neurological Activity, Pisa University Medical School, Pisa, 4Department of Neurological Neurosurgical and Behavioural Sciences, Siena University Medical School, Siena, Italy* 
