**3.6.2 ALS7**

To date, only one pedigree with ALS7 and linkage to chr20ptel-p13 has been identified (Sapp et al 2003). The family included 15 siblings, two of which were affected by an autosomal dominantly inherited form of ALS with mid-life onset and a rapid disease course of less than 2 years. The authors found probable linkage to a 6.25cM region of chr20 though more individuals from this pedigree are needed to confirm the findings (Sapp et al 2003).
