**4. Analytical methods tailored to asymmetric transfer hydrogenation**

For the purpose of monitoring of the reaction and determination of *ee* of the reaction, several effective methods were developed. Kinetic study of hydrogenation can be realized in NMR spectrometer [11] and for the determination of *ee* method using derivatization of the sample followed by the determination of diastereoisomers using gas chromatography [12] can be applied.
